Join Us

We seek self-motivated candidates with a Ph.D. or equivalent degree with strong and independent research experiences in cell biology, molecular biology, biochemistry, or mouse model systems. Interested candidates should email a CV and the names of two references to

miijima@jhmi.edu and/or hsesaki@jhmi.edu.

As members of Johns Hopkins University and of the scientific community, we acknowledge the harm perpetuated through systemic injustice and discrimination.

 

Our laboratory is committed to:

  • building a research group with respect and inclusion.

  • treating each other as equals.

  • providing a safe environment where everyone can express their opinion.

  • taking responsibility to remain unbiased.

Iijima

Cells sense environments with extreme accuracy and control their behaviors and metabolism in the human body. The Iijima laboratory studies how cells sense and respond to extracellular chemicals, such as hormones, growth factors, and cytokines, through GPCRs and receptor tyrosine kinases. We focus on intracellular signaling transduction mechanisms controlled by PI3-kinase, PTEN, small GTPases, mTORC2, and AKT using Dictyostelium discoideum, mammalian cell culture, and mouse models to discover fundamental biology and translate knowledge to the development of therapeutic interventions for human diseases, including cancer and diabetes.
 

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Sesaki

The Sesaki laboratory studies how organelles such as mitochondria and the ER orchestrate their structure, dynamics, and function. We use a wide range of approaches including protein-lipid biochemistry, molecular biology, and cutting-edge microscopy to discover fundamental biology and mouse models to translate the knowledge to the development of therapeutic interventions for diseases, including diabetes, neurodegeneration, and cancer.